Global Orthobiologics Market by Type (Bone Graft Substitutes, Bone Allografts, Bone Growth Factors & Spinal Stimulation, Stem Cell Therapy, Viscosupplementation) by End-User (Hospitals, Orthopedic Clinics, Other End-Users) – Global Analysis & Forecast to 2019

The report analyzes the global orthobiologics market by product, end-user, and geography. The global orthobiologics market has been further classified on the basis of products into five main types, such as bone graft substitutes, bone allografts, stem cell therapy, bone growth factor and spinal stimulation, and viscosupplementation. On the basis of end-users, the market has been segmented into hospitals, orthopedic clinics, and other end-users.

North America constitutes more than half of the global orthobiologics market, by registering a market share of 51.2%. This dominance is attributed to various factors such as increasing aging population, higher healthcare expenditure, and wide acceptance of orthobiologics products in the U.S.  Asia is considered as the fastest growing region in the global orthobiologics market due to the incessant rise in aging population and exponential increase in the cases of diabetes.

The awareness among people has started to rise owing to the benefits associated with orthobiologics that include faster bone healing, reduction in the number of hospital visits, and most importantly quicker recovery. There is an increased awareness among people with respect to the technological advancements in this field. Product launches are also a major contributing factor in the propelling the growth of the orthobiologic market. For instance, in February 2012, Zimmer, Inc. announced the launch of Chondrofix osteochondral allograft, a product that helps to treat osteochondral lesions using a single stage process.

This report highlights the market share analysis, by revenue, of the top companies covered in this report. These numbers are obtained based on key facts, annual financial information from SEC filings, annual reports and interviews with industry experts, key opinion leaders such as CEOs, directors, and marketing executives. In addition to this, the report also profiled key players of the market on various parameters, such as business overview, financial overview, product portfolio, business strategies, and recent developments. Some of the key market players of the global orthobiologics market include Biomet, Inc. (U.S.), Medtronic, Plc. (U.S.), Integra Life Sciences Corporation (U.S.), Stryker Corporation (U.S.), Zimmer, Inc. (U.S.), DePuy Synthes (U.S.), Tornier, Inc. (Netherlands), NuVasive, Inc. (U.S.), Exactech, Inc. (U.S.), Globus Medical, Inc. (U.S.), and Wright Medical Technology, Inc. (U.S.).

Table of Contents

1 Introduction (Page No. - 11)
    1.1 Objectives of the Study
    1.2 Market Segmentation & Coverage
    1.3 Stakeholders

2 Research Methodology (Page No. - 13)
    2.1 Integrated Ecosystem of Orthobiologics Market
           2.1.1 Top-Down Approach
           2.1.2 Bottom-Up Approach
           2.1.3 Macroindicator-Based Approach
    2.2 Assumptions

3 Executive Summary (Page No. - 19)

4 Market Overview (Page No. - 21)
    4.1 Introduction
    4.2 Market Drivers and Inhibitors
    4.3 Key Market Dynamics

5 Orthobiologics Market, By Product (Page No. - 25)
    5.1 Introduction
    5.2 Global Orthobiologics Market: Product Comparison With Parent Market
    5.3 Global Bone Graft Substitutes Market, By Geography
    5.4 Global Bone Allografts Market, By Geography
    5.5 Global Stem Cell Therapy Market, By Geography
    5.6 Global Bone Growth Factor and Spinal Stimulation Market, By Geography
    5.7 Global Viscosupplementation Market, By Geography

6 Orthobiologics Market, By End-User (Page No. - 33)
    6.1 Introduction
    6.2 Global Orthobiologics Market Hospitals Market, By Geography
    6.3 Global Orthopedic Clinics Market, By Geography
    6.4 Global Orthobiologics Other End-Users Market, By Geography

 
7 Orthobiologics Market, By Geography (Page No. - 38)
    7.1 Introduction
    7.2 North America Orthobiologics Market
           7.2.1 North America Orthobiologics Market, By Product
           7.2.2 North America Orthobiologics Market, By End-User
    7.3 Europe Orthobiologics Market
           7.3.1 Europe Orthobiologics Market, By Product
           7.3.2 Europe Orthobiologics Market, By End-User
    7.4 Asia Orthobiologics Market
           7.4.1 Asia Orthobiologics Market, By Product
           7.4.2 Asia Orthobiologics Market, By End-User
    7.5 Rest of the World (Row) Orthobiologics Market
           7.5.1 RoW Orthobiologics Market, By Product
           7.5.2 RoW Orthobiologics Market, By End-User

8 Orthobiologics Market: Competitive Landscape (Page No. - 55)
    8.1 Orthobiologics Market: Company Share Analysis
    8.2 Company Presence in Orthobiologics Market, By Product
    8.3 Mergers & Acquisitions
    8.4 New Product Launches
    8.5 Expansions
    8.6 Agreements
    8.7 Other Developments

9 Orthobiologics Market, By Company (Page No. - 61)
(Overview, Financials, Products & Services, Strategy, and Developments)*
    9.1 Biomet, Inc.
    9.2 Medtronic PLC
    9.3 Integra Life Sciences Corporation
    9.4 Stryker Corporation
    9.5 Zimmer, Inc.
    9.6 Depuy Synthes (Johnson & Johnson Family of Companies)
    9.7 Tornier, Inc.
    9.8 Nuvasive, Inc.
    9.9 Exactech, Inc.
    9.10 Globus Medical Inc.
    9.11 Wright Medical Technology, Inc.
*Details on Overview, Financials, Product & Services, Strategy, and Developments Might Not be Captured in Case of Unlisted Company

10 Appendix (Page No. - 95)
     10.1 Customization Options
             10.1.1 Regulatory Framework
             10.1.2 Epidemiology Data
             10.1.3 Surgeons/Physicians Perception Analysis
             10.1.4 Impact Analysis
     10.2 Related Reports
     10.3 Introducing RT: Real Time Market Intelligence
             10.3.1 RT Snapshots

List of Tables (42 Tables)

Table 1 Global Orthobiologic Peer Market Size, 2014 (USD MN)
Table 2 Global Orthobiologic Market: Macroindicator, By Country, 2014
Table 3 Global Orthobiologic Market: Comparison With Parent Market,2013-2019 (USD MN)
Table 4 Global Orthobiologic Market: Drivers and Inhibitors
Table 5 Global Orthobiologic Market, By Product, 2013-2019 (USD MN)
Table 6 Global Orthobiologic Market, By Product, 2013-2019 (USD MN)
Table 7 Global Orthobiologic Market, Product Comparison With Parent Market, 2013–2019 (USD MN)
Table 8 Global Bone Graft Substitutes Market, By Geography, 2013–2019 (USD MN)
Table 9 Global Bone Allografts Market, By Geography, 2013-2019 (USD MN)
Table 10 Global Stem Cell Therapy Market, By Geography, 2013-2019 (USD MN)
Table 11 Global Stem Cell Therapy Market, By Geography, 2013-2019 (USD MN)
Table 12 Global Viscosupplementation Market, By Geography, 2013–2019 (USD MN)
Table 13 Global Orthobiologic Market Size, By End-User, 2013-2019 (USD MN)
Table 14 Global Orthobiologic Market in Hospitals, By Geography,2013-2019 (USD MN)
Table 15 Global Orthopedic Market in Clinics, By Geography, 2013-2019 (USD MN)
Table 16 Global Orthobiologic Market in Other End-Users, By Geography,2013 - 2019 (USD MN)
Table 17 Global Orthobiologic Market, By Geography, 2013-2019 (USD MN)
Table 18 North America Orthobiologic Market, By Product, 2013-2019 (USD MN)
Table 19 North America Orthobiologic Market, By End-User, 2013-2019 (USD MN)
Table 20 Europe Orthobiologic Market, By Product, 2013-2019 (USD MN)
Table 21 Europe Orthobiologic Market , By End-User, 2013-2019 (USD MN)
Table 22 Asia Orthobiologic Market, By Product, 2013-2019 (USD MN)
Table 23 Asia Orthobiologic Market, By End-User, 2013-2019 (USD MN)
Table 24 RoW Orthobiologic Market, By Product, 2013-2019 (USD MN)
Table 25 RoW Orthobiologic Market, By End-User, 2013-2019 (USD MN)
Table 26 Orthobiologic Market: Company Share Analysis, 2013 (%)
Table 27 Global Orthobiologic Market: Mergers & Acquisitions
Table 28 Global Orthobiologic Market: New Product Launches
Table 29 Global Orthobiologic Market: Expansions
Table 30 Global Orthobiologic Market: Agreements
Table 31 Global Orthobiologics Market: Other Developments
Table 32 Biomet, Inc.: Key Financials, 2011-2013 (USD MN)
Table 33 Medtronic, PLC. : Key Financials, 2009-2013 (USD MN)
Table 34 Integra Life Sciences Corporation: Key Financials, 2010-2013 (USD MN)
Table 35 Stryker Corporation: Key Financials, 2009-2013 (USD MN)
Table 36 Zimmer, Inc.: Key Financials, 2009-2013 (USD MN)
Table 37 Depuy Synthes: Key Financials, 2011-2013 (USD MN)
Table 38 Tornier, Inc.: Key Financials, 2009-2013 (USD MN)
Table 39 Nuvasive, Inc.: Key Financials, 2009-2013 (USD MN)
Table 40 Exactech, Inc.: Key Financials, 2009-2013 (USD MN)
Table 41 Globus Medical, Inc.: Key Financials, 2009-2013 (USD MN)
Table 42 Wright Medical Technology, Inc.: Key Financials, 2011-2013 (USD MN)

List of Figures (63 Figures)

Figure 1 Global Orthobiologic Market: Segmentation & Coverage
Figure 2 Orthobiologics Market: Integrated Ecosystem
Figure 3 Top-Down Approach
Figure 4 Bottom-Up Approach
Figure 5 Macroindicator-Based Approach
Figure 6 Global Orthobiologic Market Snapshot
Figure 7 Global Orthobiologic Market: Comparison With Parent Market
Figure 8 Global Orthobiologic Products, By Geography, 2014 (USD MN)
Figure 9 Global Orthobiologic Market, By Product, 2013-2019 (USD MN)
Figure 10 Global Orthobiologic Market: Product Comparison With Parent Market, 2013–2019 (USD MN)
Figure 11 Global Bone Graft Substitutes Market, By Geography, 2013–2019 (USD MN)
Figure 12 Global Bone Allografts Market, By Geography, 2013 - 2019 (USD MN)
Figure 13 Global Stem Cell Therapy Market, By Geography, 2013-2019 (USD MN)
Figure 14 Global Bone Growth Factor and Spinal Stimulation Market,By Geography, 2013-2019 (USD MN)
Figure 15 Global Viscosupplementation Market, By Geography, 2013–2019 (USD MN)
Figure 16 Global Orthobiologic Market, By End-User, 2013-2019 (USD MN)
Figure 17 Global Orthobiologic Market in Hospitals, By Geography,2013-2019 (USD MN)
Figure 18 Global Orthopedic Market in Clinics, By Geography, 2013-2019 (USD MN)
Figure 19 Global Orthobiologic Market in Other End-Users, By Geography,2013-2019 (USD MN)
Figure 20 Global Orthobiologic Market Growth Analysis, By Geography,2014-2019 (USD MN)
Figure 21 North America Orthobiologic Market Overview, 2014 & 2019 (%)
Figure 22 North America Orthobiologic Market, By Product, 2013-2019 (USD MN)
Figure 23 North America: Orthobiologic Market: Product Snapshot
Figure 24 North America Orthobiologic Market, By End-User, 2013-2019 (USD MN)
Figure 25 North America Orthobiologic Market: End-User Snapshot (%)
Figure 26 Europe Orthobiologic Market Overview, 2014 & 2019 (%)
Figure 27 Europe Orthobiologic Market, By Product, 2013-2019 (USD MN)
Figure 28 Europe Orthobiologic Market: Product Snapshot
Figure 29 Europe Orthobiologic Market, By End-User, 2013-2019 (USD MN)
Figure 30 Europe: Orthobiologic Market: End-User Snapshot
Figure 31 Asia Orthobiologic Market Overview, 2014 & 2019 (%)
Figure 32 Asia Orthobiologic Market, By Product, 2013-2019 (USD MN)
Figure 33 Asia Orthobiologic Market: Product Snapshot
Figure 34 Asia Orthobiologic Market, By End-User, 2013-2019 (USD MN)
Figure 35 Asia Orthobiologic Market: End-User Snapshot
Figure 36 RoW Orthobiologic Market Overview, 2014 & 2019 (%)
Figure 37 RoW Orthobiologic Market, By Product, 2013-2019 (USD MN)
Figure 38 RoW Orthobiologic Market: Product Snapshot
Figure 39 RoW Orthobiologic Market, By End-User, 2013-2019 (USD MN)
Figure 40 RoW Orthobiologic Market: End-User Snapshot
Figure 41 Orthobiologic Market: Company Share Analysis, 2014 (%)
Figure 42 Orthobiologic: Company Product Coverage, 2013
Figure 43 Biomet, Inc.: Revenue Mix, 2013 (%)
Figure 44 Contribution of Spine, Bone Healing, and Microfixation Segment Towards Company Revenues, 2011-2013 (USD MN)
Figure 45 Medtronic, PLC.  Revenue Mix, 2013 (%)
Figure 46 Contribution of Restorative Therapies Group Segment Towards Company Revenues, 2009-2013 (USD MN)
Figure 47 Integra Life Sciences Corporation Revenue Mix, 2013 (%)
Figure 48 Contribution of U.S. Spine and Other Segment Towards Company Revenues, 2010-2013 (USD MN)
Figure 49 Stryker Corporation Revenue Mix, 2013 (%)
Figure 50 Contribution of Neurotechnology and Spine Segment Towards Company Revenues, 2009-2013 (USD MN)
Figure 51 Zimmer, Inc.: Revenue Mix, 2013 (%)
Figure 52 Contribution of Surgical and Other Segment Towards Company Revenues, 2009-2013 (USD MN)
Figure 53 Depuy Synthes Revenue Mix, 2013 (%)
Figure 54 Tornier, Inc.: Revenue Mix 2013 (%)
Figure 55 Contribution of Extremities Segment Towards Company Revenues,2009-2013 (USD MN)
Figure 56 Nuvasive, Inc.: Revenue Mix 2013 (%)
Figure 57 Contribution of Biologics Segment Towards Company Revenues,2009 - 2013 (USD MN)
Figure 58 Exactech, Inc.: Revenue Mix 2013 (%)
Figure 59 Contribution of Biologics & Spine Segment Towards Company Revenues, 2009-2013 (USD MN)
Figure 60 Globus Medical, Inc.: Revenue Mix 2013 (%)
Figure 61 Contribution of Disruptive Technology Segment Towards Company Revenues, 2009-2013 (USD MN)
Figure 62 Wright Medical Technology, Inc.: Revenue Mix 2013 (%)
Figure 63 Contribution of Biologics Segment Towards Company Revenues, 2011 - 2013 (USD MN)

Orthobiologics are defined as the substances of biological origin that facilitate the bone healing process with proficiency. The normal bone healing process involves repositioning of the injured or fractured bone surgically or by immobilization of the dislocated bone, thereby waiting for the body’s normal bone healing process to heal the bone and reposition it in its appropriate place. The importance of orthobiologics is highlighted due to the fact that orthobiologics products accelerate the natural bone healing process, and ensure faster bone healing without facing any immunological barriers. 

Orthobiologics have been experiencing substantial growth since 2012 in terms of technological advancements, owing to the rise in the number of osteoarthritis and osteoporosis patients across all regions around the world. . It is estimated that approximately 10% of the global population suffers from arthritis. Orthobiologics provide an effective alternative to mechanical bone implants, which take a relatively longer time to reposition and heal the bone. Orthobiologics involve products that are derived from the patient’s own body. Due to this feature, the healing process gets catalyzed and the pace of the bone healing quickens.

The global orthobiologics market was valued at $5,712.4 million in 2014, and is expected to reach $7,900.2 million by 2019, at a CAGR of 6.7% from 2014 to 2019. The global orthobiologics market has been segmented on the basis of product, end-user, and geography. On the basis of products, the market is classified into bone graft substitutes, bone allografts, stem cell therapy, bone growth factor & spinal stimulation, and viscosupplementation. The market has been further segmented on the basis of end-users into hospitals, orthopedic clinics, and other end-users. According to geographical segmentation, the global orthobiologics market is sub-divided into North America, Europe, Asia, and rest of the world (RoW).

The key players operating in this market are Biomet, Inc. (U.S.), Medtronic, Plc. (U.S.), Integra Life Sciences Corporation (U.S.), Stryker Corporation (U.S.), Zimmer, Inc. (U.S.), Tornier, Inc. (The Netherlands), NuVasive (U.S.), Exactech, Inc. (U.S.), Globus Medical, Inc. (U.S.), and Wright Medical Technology, Inc. (U.S.), among others.